A PIONEERING DEVICE WORLDWIDE

AMPLATZER™ PFO Occluder created the category of PFO occlusion, sustained leadership over decades of use, and was the first device supported by positive PFO trial results.

WHY IS AMPLATZER PFO OCCLUDER RELIED UPON BY THOUSANDS OF PHYSICIANS AROUND THE WORLD?

We set the standard

WE SET THE STANDARD

  • Pioneered treatment with a PFO-specific device
  • Over 100,000 device implanted globally

We raise the bar

WE RAISE THE BAR: THE LANDMARK RESPECT TRIAL1

  • Most extensive patient follow-up, >2X more than other PFO trials
  • Only trial to include patients on anticoagulation therapy, a real-world cross-section of patients

We demostrate excellence

WE DEMONSTRATE EXCELLENCE

  • ZERO device erosions, thrombus, or embolization events in SIX* published trials with 990 patients1-6
  • 94.2% effective closure rates at 6 months1

OFTEN IMITATED, NEVER MATCHED

INDUSTRY-LEADING DEVICE. DEVELOPED SPECIFICALLY FOR THE TREATMENT OF PFO CLOSURE.

DESIGN ADVANTAGES THAT MAKE THE DIFFERENCE

PFO Occluder

*On commonly used sizes (25mm and 35mm devices)
† Effective closure

ONE STEP AHEAD:
MINIMIZING COMPLEXITY IN CLOSURE

One Step Ahead

One Step Ahead

UNIQUE SELF-EXPANDING DISCS:

Linked by a short-connecting waist, the discs align to the PFO without an additional “locking” step.

LOW PROFILE DELIVERY:

8 F & 9 F introducer sheaths for multiple sizes (18, 25, 35 mm) enables treatment of patients with smaller vasculature.

FULLY RECAPTURABLE AND REPOSITIONABLE:

Allows confirmation of device placement prior to final release of the device.

LEARN ABOUT THE PROCEDURE

References:

  1. Søndergaard L, Kasner SE, Rhodes JF, et al. Patent foramen ovale closure or antiplatelet therapy for cryptogenic stroke. N Engl J Med. 2017; 377: 1033-42.
  2. Saver JL, Carroll JD, Thaler DE, et al. Long-term outcomes of patent foramen ovale closure or medical therapy after stroke. N Engl J Med. 2017; 377: 1022-32.
  3. Mas J-L, Derumeaux G, Guillon B, et al. Patent foramen ovale closure or anticoagulation vs. antiplatelets after stroke. N Engl J Med. 2017;377:1011-21 and supplementary appendix.